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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AURKC
All Species:
26.06
Human Site:
T39
Identified Species:
44.1
UniProt:
Q9UQB9
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQB9
NP_001015878.1
309
35591
T39
S
P
A
M
R
R
L
T
V
D
D
F
E
I
G
Chimpanzee
Pan troglodytes
XP_001142357
309
35587
T39
S
P
A
M
R
R
L
T
I
D
D
F
E
I
G
Rhesus Macaque
Macaca mulatta
XP_001098364
471
52859
K201
S
P
A
M
R
R
L
K
I
D
D
F
E
I
G
Dog
Lupus familis
XP_849906
346
39574
T73
N
F
S
M
R
S
F
T
I
D
D
F
E
I
G
Cat
Felis silvestris
Mouse
Mus musculus
O88445
282
32888
K36
R
V
Y
L
A
R
L
K
E
N
H
F
I
V
A
Rat
Rattus norvegicus
O55099
343
39216
T76
S
Q
S
R
Q
P
F
T
I
D
N
F
E
I
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521399
303
34973
P37
D
D
F
D
I
G
R
P
L
G
K
G
K
F
G
Chicken
Gallus gallus
XP_425725
409
46456
S143
E
T
K
K
R
Q
W
S
L
D
D
F
E
I
G
Frog
Xenopus laevis
Q6GPL3
368
41997
T96
E
A
P
K
R
K
F
T
I
D
D
F
D
I
G
Zebra Danio
Brachydanio rerio
Q6NW76
320
36928
S49
K
S
N
S
K
V
L
S
I
D
D
F
D
I
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKN7
329
38282
S38
N
M
C
L
K
M
M
S
H
D
A
Y
G
Q
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O01427
305
34731
P35
N
D
F
E
I
G
R
P
L
G
K
G
K
F
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q683C9
282
32738
L35
G
K
F
G
H
V
Y
L
A
R
E
K
R
S
D
Baker's Yeast
Sacchar. cerevisiae
P38991
367
42927
S100
L
P
K
F
K
S
L
S
L
D
D
F
E
L
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
63.4
70.5
N.A.
72.4
67.3
N.A.
64.7
52.3
58.1
65.3
N.A.
43.1
N.A.
54.6
N.A.
Protein Similarity:
100
100
64.7
78.9
N.A.
82.5
79.3
N.A.
78.3
62.3
71.1
78.7
N.A.
62.6
N.A.
68.9
N.A.
P-Site Identity:
100
93.3
86.6
60
N.A.
20
46.6
N.A.
6.6
46.6
46.6
40
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
93.3
80
N.A.
40
73.3
N.A.
20
66.6
66.6
66.6
N.A.
46.6
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
56.3
38.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70.8
55.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
22
0
8
0
0
0
8
0
8
0
0
0
8
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
15
0
8
0
0
0
0
0
72
58
0
15
0
8
% D
% Glu:
15
0
0
8
0
0
0
0
8
0
8
0
50
0
0
% E
% Phe:
0
8
22
8
0
0
22
0
0
0
0
72
0
15
0
% F
% Gly:
8
0
0
8
0
15
0
0
0
15
0
15
8
0
79
% G
% His:
0
0
0
0
8
0
0
0
8
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
15
0
0
0
43
0
0
0
8
58
0
% I
% Lys:
8
8
15
15
22
8
0
15
0
0
15
8
15
0
0
% K
% Leu:
8
0
0
15
0
0
43
8
29
0
0
0
0
8
0
% L
% Met:
0
8
0
29
0
8
8
0
0
0
0
0
0
0
0
% M
% Asn:
22
0
8
0
0
0
0
0
0
8
8
0
0
0
0
% N
% Pro:
0
29
8
0
0
8
0
15
0
0
0
0
0
0
8
% P
% Gln:
0
8
0
0
8
8
0
0
0
0
0
0
0
8
0
% Q
% Arg:
8
0
0
8
43
29
15
0
0
8
0
0
8
0
0
% R
% Ser:
29
8
15
8
0
15
0
29
0
0
0
0
0
8
0
% S
% Thr:
0
8
0
0
0
0
0
36
0
0
0
0
0
0
0
% T
% Val:
0
8
0
0
0
15
0
0
8
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
8
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _